The fundamental vision of PillPack is backed up by years of research that suggest accessible medical information, improved packaging and readily available consultation can help people be adherent to a prescribed medication regimen. Additional studies confirm that adherence improves overall health while lack of adherence can negatively impact outcomes.
Key studies and references we consulted in developing PillPack:
Duru OK, Schmittdiel JA, Dyer WT, Parker MM, Uratsu CS, Chan J, Karter AJ. Mail-Order Pharmacy Use and Adherence to Diabetes-Related Medications. American Journal of Managed Care. 2010l 16(1): 33-40.
Field TS, Mazor KM, Briesacher B, DeBellis KR, Gurwitz JH. Adverse Drug Events Resulting from Patient Errors in Older Adults. Journal of the American Geriatrics Society. 2007; 55: 271-276.
Lee JK, Grace KA, Taylor AJ. Effect of a Pharmacy Care Program on Medication Adherence and Persistence, Blood Pressure, and Low-Density Lipoprotein Cholesterol A Randomized Controlled Trial. Journal of the American Medical Association. 2006; 296 (21):2563-2571.
Viswanathan M, Golin CE, Jones CD, Ashok M, Blalock SJ, Wines RC, Coker-Schwimmer EJ, Rosen DL, Sista P, Lohr KN. Interventions to improve adherence to self-administered medications for chronic diseases in the United States: a systematic review. Annals of Internal Medicine. 2012;157(11):785-95.
Zedler BK, Kakad P, Colilla S, Murrelle L, Shah NR. Does packaging with a calendar feature improve adherence to self-administered medication for long-term use? A systematic review. 2011; 33(1):62–73.
Thinking Outside the Pillbox: A System-wide Approach to Improving Patient Medication Adherence for Chronic Disease. New England Healthcare Association. 2009.